Showing posts with label Toxicity. Show all posts
Showing posts with label Toxicity. Show all posts

Friday, April 18, 2008

Brunfelsia Plant Proves Life-Threatening to Dogs

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According to a recently published study by Dr. Safdar Khan, veterinary toxicologist for the ASPCA Animal Poison Control Center (APCC), dogs seem to be particularly attracted to the seeds and berries of the Brunfelsia plant, commonly known as “morning, noon and night” and “yesterday, today and tomorrow.” In fact, canines are most susceptible to poisoning by this gardener’s favorite, aptly named for its fragrant flowers that bloom in vivid purple and gradually change to lavender before fading to white.


From 2001 to 2006, the APCC treated 38 cases of Brunfelsia poisoning involving 42 dogs. One California hound experienced stiff limbs and excessive drooling after ingesting several seeds from the plant. A terrier puppy from Florida developed life-threatening seizures after consuming another part of the plant. With help from the APCC and the services of a local emergency veterinarian, the puppy eventually made a full recovery. However, three of the cases proved fatal.


“Brunfelsia toxicity can progress very rapidly to a potentially lethal situation, so it’s critical that pet parents seek immediate veterinary care,” says Dr. Khan. “If pets consume any part of the plant, they can become ill within hours and develop gastrointestinal problems such as vomiting and diarrhea, as well as tremors, seizures and muscle rigidity that makes the animal appear to be in a ‘sawhorse’ stance.”


The most commonly affected breeds are Labradors and golden retrievers, who, because they tend to be very active, may be more likely to get to the plant’s seeds and leaves.


If you have Brunfelsia in your home, please keep the plant in an area where pets can’t reach it, or replace it with a nontoxic alternative. Pet parents should remember to take precautions against the many plants and flowers that can prove harmful to their animals.

The following video from the ASPCA features 17 other common poisonous plants:


Information from the ASPCA Pressroom.

Thursday, March 13, 2008

The Dangers Associated With Raisins

Written by: Laurinda Morris, DVM
Danville Veterinary Clinic
Danville, Ohio

This week I had the first case of raisin toxicity ever seen at MedVet. My patient was a 56-pound, 5 yr old male neutered lab mix that ate half a canister of raisins sometime between 7:30 AM and 4:30 PM on Tuesday. He started with vomiting, diarrhea and shaking about 1AM on Wednesday but the owner didn't call my emergency service until 7AM.

I had heard somewhere about raisins AND grapes causing acute Renal failure but hadn't seen any formal paper on the subject. We had her bring the dog in immediately. In the meantime, I called the ER service at MedVet, and the doctor there was like me - had heard something about it, but.... Anyway, we contacted the ASPCA National Animal Poison Control Center and they said to give I V fluids at 1 1/2 times maintenance and watch the kidney values for the next 48-72 hours.

The dog's BUN (blood urea nitrogen level) was already at 32 (normal less than 27) and creatinine over 5 (1.9 is the high end of normal). Both are monitors of kidney function in the bloodstream. We placed an IV catheter and started the fluids. Rechecked the renal values at 5 PM and the BUN was over 40 and creatinine over 7 with no urine production after a liter of fluids. At the point I felt the dog was in acute renal failure and sent him on to MedVet for a urinary catheter to monitor urine output overnight as well as overnight care.

He started vomiting again overnight at MedVet and his renal values have continued to increase daily. He produced urine when given lasix as a diuretic. He was on 3 different anti-vomiting medications and they still couldn't control his vomiting. Today his urine output decreased again, his BUN was over 120, his creatinine was at 10, his phosphorus was very elevated and his blood pressure, which had been staying around 150, skyrocketed to 220.. He continued to vomit and the owners elected to euthanize.

This is a very sad case - great dog, great owners who had no idea raisins could be a toxin. Please alert everyone you know who has a dog of this very serious risk. Poison control said as few as 7 raisins or grapes could be toxic. Many people I know give their dogs grapes or raisins as treats including our ex-handler's. Any exposure should give rise to immediate concern.

Even if you don't have a dog, you might have friends who do. This is worth passing on to them.

Confirmation from Snopes: http://www.snopes.com/critters/crusader/raisins.asp